Why SpaceOAR® Hydrogel?

SpaceOAR Hydrogel The Number One Prostate-Rectum Spacer in the World

SpaceOAR hydrogel is a unique, water-based hydrogel which lasts for the duration of radiation treatment (up to three months), and is then naturally absorbed leaving the body through the patient’s urine within six months. Hydrogel has been used in other implants such as surgical sealants used on the eye, brain and spine. Studies have shown that the material is biocompatible and can be used safely in the body.

The first 5-year quality of life results in a group of prostate cancer patients treated with a hydrogel spacer demonstrate excellent treatment tolerability, in particular regarding bowel problems. – Michael Pinkawa, MD, PhD

1. Received positive NICE guidance in 2017
The clinical evidence and product procedure of utilising a biodegradable spacer to reduce rectal toxicity have been reviewed and approved by the National Institute for Health Care and Excellence under procedural guidance code IPG590.

2. Minimally Invasive
Implanted with one 18G needle, it does not require a surgical scalpel or dilator. SpaceOAR hydrogel can be inserted with general or local anaesthesia, facilitating a day case procedure.2

3. Consistent Space
SpaceOAR is a soft hydrogel that creates on average over 1cm of space for the duration of radiotherapy.3

Injection of a filling material in the prostate-rectum interspace prior to primary EBRT of the prostate is an elegant way to effectively reduce dose to the anterior rectal wall. – Wolf et al

Data That Matters

SpaceOAR hydrogel is the number one prostate-rectum spacer, supported by clinical evidence and established users:

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  1. Michael Pinkawa, MD, PhD, Vanessa Berneking, MD,Marsha Schlenter, MD, Barbara Krenkel, MD, and Michael J. Eble, MD, PhD. Quality of Life After Radiation Therapy for Prostate Cancer With a Hydrogel Spacer: 5-Year Results. Int J Radiation Oncol Biol Phys, Vol. 99, No. 2, pp. 374e377, 2017
  2. MONTOYA J, GROSS E, KARSH L. How I Do It: Hydrogel spacer placement in men scheduled to undergo prostate radiotherapy. Can J Urol 2018; 25(2):9288-9293.
  3. Mariados N, et al; Hydrogel spacer prospective multicenter randomized controlled pivotal trial: dosimetric and clinical effects of perirectal spacer application in men undergoing prostate image guided intensity modulated radiation therapy. International Journal of Radiation Oncology Biology and Physics (2015); 92(5): 971-977
  4. Wolf et al. Comparison of two different rectal spacers in prostate cancer external beam radiotherapy in terms of rectal sparing and volume consistency. 2015 Aug;116(2):221-5.